But, that's the problem, I think there's potentially a greater disconnect with this device than with a paper/ scanner/ tablet combination. After all, you are dealing with a tool that gives you only one form of immediate feedback, a ballpoint line on paper, and then a set of vectors derived from the sketch that may still be subject to extremely accurate calibration. You're still taking a punt on what you end up with, especially if you're talking about combining a number of layers. The benefit I find of working directly on screen with a tablet is that you have an entire suite of tools to hand and the ability to more fully edit and respond immediately to issues as they arise. Admittedly I've been working with tablets for a long time now, but I no longer struggle at all with the hand/ eye disconnect and I'd have to say as difficult as it is to get to grips with, initially, it's well worth making the effort as it gives you more choice and fidelity in the monitor you use. Paper, pencil and scanner, to my mind, is much more direct (in terms of What You See Is What You Get).
It largely comes down to adaptation though. I'm sure many peolple will adopt this pen and use it to astonishing effect.